Lonesome George was the famed last representative of a giant tortoise species once found on the Galapagos island of Pinta. Image credit: Mark Putney

Famous giant tortoise DNA may hold fountain of youth: UCBO

After Lonesome George’s death he still provides clues to longer life

Ever since Darwin’s first steps on the Galapagos Islands, understanding the adaptations that offer the giant tortoise its extended lifespan has been a tantalizing scientific pursuit.

And now, new research by an international team including researchers from UBC’s Okanagan campus has used the DNA from one famous giant tortoise to uncover the genes that are associated with their longevity. The discovery provides clues to better understand aging in humans and may help preserve the species says Michael Russello, study co-author and biology professor at UBC Okanagan.

“Giant tortoises are among the longest living vertebrate animals and have become an interesting model for studying longevity and age related-disease,” said Russello. “Even though they’re one of few animals that can live longer than 100 years, there has been surprisingly little research into the giant tortoise genome.”

RELATED: UBCO and BCIT team up to brew cannabis-infused beverages

To help identify the genes that give the giant tortoise its extended lifespan, the researchers compared the complete DNA sequence from two long-lived giant tortoises. They used samples from Lonesome George—the famed last representative of a species once found on the Galapagos island of Pinta—and from another giant tortoise species found on the Aldabra atoll, a coral island in the Indian Ocean.

RELATED: UBCO sociology class calls on Kelowna Chiefs to change “derogatory” name

By comparing the giant tortoise genomes with those from other species, including humans, they found interesting variation within genes linked to DNA repair, immune response, and cancer suppression not possessed by shorter-lived vertebrates. None of those genomic variants had been previously associated with aging, offering new avenues for further study.

While individual tortoises have remarkable longevity, Russello says the Galapagos giant tortoises do not, with all living species considered threatened or endangered. He says the results of their study could provide clues into the biological processes and adaptations that gave rise to giant tortoises in the first place, while helping to better protect these animals on the verge of disappearing altogether.

“Lonesome George was a very interesting character in his own right, embodying the plight of endangered species until his death in 2012,” said Russello. “While he inspired many while he was alive, his legacy now lives on through a story written in his DNA.”

To report a typo, email:
newstips@kelownacapnews.com
.


@KelownaCapNews
newstips@kelownacapnews.com

Like us on Facebook and follow us on Twitter.

Get local stories you won't find anywhere else right to your inbox.
Sign up here

Just Posted

New Alberta forward joins Vancouver Giants’ ranks

new left-handed 18-year-old is a familiar face to Giants head coach Michael Dyck

Langley Advance Times Arts Calendar: Feb. 21, 2020 edition

The arts calendar is published Fridays and the community calendar is in the Wednesday print edition

LETTER: Baffled by warning signs in Langley

Reader sees electronic signage as a waste of money and ‘not very useful’

Mugging with airsoft gun results in Langley school lockdown

Police found the weapon and a stolen phone later

Get your say on Langley Township’s budget

Surveys are available online now

VIDEO: B.C. senior recalls ‘crazy’ wartime decision to grab bear cub from den

Henry Martens – now 96 – says he was lucky to be alive after youthful decision to enter a bear’s den

‘A bag full of garbage every 15 metres’: Surrey industrial area filled with trash

Local workers looking to recruit business, raise funds to help dispose of litter

Cheapest in B.C.: Penticton gas prices dip below $1 per litre

Two stores in Penticton have gas below a dollar.

Brand new Tesla crashes into Surrey store front, mounts gas line

Driver was heading to the Autoplan store, straight off the lot

Loans or gifts? Judge rules woman must pay B.C. man back $7K

B.C. judge rules that woman must pay back more than $7,000 in advanced funds to man

VIDEO: Outpouring of worldwide support for bullied Australian boy

Australian actor Hugh Jackman said ‘you are stronger than you know, mate’

‘A horror show:’ Ex-employee shares experience at problematic Chilliwack seniors’ home

Workers are paid below industry standard at all Retirement Concepts facilities

Forest industry protests northern B.C. caribou protection deal

B.C. Mining Association supports federal-Indigenous plan

Youth-led report calls on B.C. government to create plan to end youth homelessness

There are no dedicated programs for youth homelessness at federal, provincial level, report says

Most Read